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Cat No. | Product Name | Synonyms | Targets |
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T10765 | Eragidomide | CC-90009,Cereblon modulator 1 | Apoptosis , Ligand for E3 Ligase , Molecular Glues |
Eragidomide (CC-90009; Cereblon modulator 1) is a cereblon (CRBN) E3 ligase modulator. Eragidomide specifically binds to CRBN, thereby affecting the activity of the ubiquitin E3 ligase complex. | |||
T13114 | CCR2 antagonist 4 | Teijin compound 1 | CCR |
CCR2 antagonist 4 (Teijin compound 1) is a potent and specific antagonist of CCR2(IC50s of 180 nM), and potently inhibits MCP-1-induced chemotaxis(IC50 of 24 nM). | |||
T21870 | C-021 | 4-Quinazolinamine, 2-[1,4'-bipiperidin]-1'-yl-N-cycloheptyl-6,7-dimethoxy- | CCR |
C 021 dihydrochloride is a potent CCR4 antagonist. C-021 (4-Quinazolinamine, 2-[1,4'-bipiperidin]-1'-yl-N-cycloheptyl-6,7-dimethoxy-) dihydrochloride potently inhibits functional chemotaxis in humans and mice with IC50s ... | |||
T14900 | CCR2-RA-[R] | CCR | |
CCR2-RA-[R] is a C-C chemokine receptor type 2 (CCR2) allosteric antagonist (IC50: 103 nM). | |||
T30091 | AP-22408 | UNII-3U3L5QR4KV,AC1L9I7C,AP22408,CC1 | |
AP-22408 is an inhibitor of SRC tyrosine kinase. | |||
T40342 | MC-VC-PABC-amide-PEG1-CH2-CC-885 | MC-VC-PABC-amide-PEG1-CH2-CC-885 | |
MC-VC-PABC-amide-PEG1-CH2-CC-885 is an Antibody-Drug Conjugate (ADC) utilizing a protein-degrading agent (protac molecular glue, etc.). | |||
T14894 | CC-90003 | ERK | |
CC-90003 is a selective inhibitor of ERK 1/2. It has antitumor activity. | |||
T11882 | Pulrodemstat benzenesulfonate | LSD1-IN-7 benzenesulfonate,CC-90011 benzenesulfonate | Histone Demethylase |
Pulrodemstat benzenesulfonate (CC-90011 benzenesulfonate) is a potent and orally active inhibitor of lysine specific demethylase-1 (LSD1) with anticancer activity. | |||
T14688 | BMS CCR2 22 | CCR | |
BMS CCR2 22 is a potent and selective antagonist of CCR2 with calcium flux IC50 of 18 nM, chemotaxis IC50 of 1 nM, and binding IC50 of 5.1 nM. | |||
T35829 | CC-90005 | ||
CC-90005 is a potent, selective and orally active inhibitor of protein kinase C-θ (PKC-θ), with an IC50 of 8 nM. CC-90005 shows selectivity for PKC-θ over PKC-δ (IC50=4440 nM). CC-90005 can inhibit T cell activation by I... | |||
T30774 | CC-3052 | CC3052 | |
CC-3052 is a water-soluble, highly stable thalidomide analogue that is an effective inhibitor of HIV-1 expression and activation-induced TNF-α production. CC-3052 also inhibited PHA-induced and rTNF-α induced TNF-α trans... | |||
T76732 | CC-90002 | ||
CC-90002, a humanized anti-CD47 monoclonal antibody (mAb), demonstrates high affinity for CD47, characterized by a subnanomolar dissociation constant (K d). It is utilized in the research of hematologic malignancies and ... | |||
T81793 | Minretumomab | CC-49 | |
Minretumomab (CC-49), a murine monoclonal antibody targeting TAG-72 (tumor-associated glycoprotein 72), serves a role in cancer and immunity research [1] [2]. | |||
T10716 | CCR7 Ligand 1 | CCR7-Cmp2105 | Others |
CCR7 Ligand 1 (CCR7-Cmp2105) is an allosteric Ligand and antagonist for human CC chemokine receptor 7 (CCR7) with a Kd of 3 nM. CCR7 Ligand 1, thiadiazole-dioxide ligan, suppresses arrestin binding in response to activat... | |||
T82767 | CC-3060 | ||
CC-3060 is a potent Cereblon modulator that facilitates the degradation of ZBTB16, exhibiting a DC50 of 0.47 nM in HT-1080 cells. It orchestrates ZBTB16 degradation by targeting discrete structural degrons within various... | |||
T61737 | FtsZ-IN-4 | ||
FtsZ-IN-4, an orally active inhibitor of FtsZ (filamenting temperature-sensitive mutant Z), demonstrates remarkable antibacterial activity and favorable pharmaceutical properties. With low cytotoxicity (CC 50 >20 μg/mL) ... | |||
T76547 | VMIP-II (1-21) | ||
vMIP-II (1-21), a CXCR4 antagonist, exhibits broad-spectrum interaction with both CC and CXC chemokine receptors, specifically binding to CXCR4. It competes for CXCR4 binding of 125I-SDF-1R with an IC 50 value of 190 nM ... | |||
T82994 | Anzurstobart | BMS-986351,CC-95251 | |
Anzurstobart (CC-95251; BMS-986351), a fully human monoclonal anti-SIRPα antibody with high affinity, inhibits CD47-SIRPα interaction. It potentiates macrophage-mediated phagocytosis of DLBCL cell lines in co-culture ass... | |||
T61080 | L-I-OddU | ||
L-I-OddU, a potent and selective anti-Epstein-Barr virus (EBV) agent, is a L-5'-halo-dioxolane nucleoside analogue. It demonstrates antiviral activity by effectively suppressing replicative EBV DNA and viral protein synt... | |||
T60871 | Gp120-IN-1 | ||
gp120-IN-1 (compound 4e) is a potent HIV-1 gp120 inhibitor with an CC 50 of 100.90 μM and IC 50 of 2.2 μM. gp120-IN-1 inhibitis gp120-mediated virus enter into cells. gp120-IN-1 has anti-HIV-1 activity. gp120-IN-1 has do... | |||
T21763 | Lenalidomide hydrochloride | ||
Lenalidomide hydrochloride (CC-5013 hydrochloride), a Thalidomide derivative, functions as molecular glue and serves as an orally active immunomodulator. As a ligand for the ubiquitin E3 ligase cereblon (CRBN), it facili... | |||
T39258 | Pulrodemstat | LSD1-IN-7,CC-90011 | |
Pulrodemstat (CC-90011) is a highly potent and selective inhibitor of lysine specific demethylase-1 (LSD1). It exhibits a reversible mode of action and can be administered orally. With an impressive IC50 of 0.25 nM, Pulr... | |||
T60714 | Gp120-IN-2 | ||
gp120-IN-2 (compound 4i) exhibits anti-HIV-1 activity which is a potent inhibitor of HIV-1 gp120 with an IC 50 of 7.5 μM and CC 50 of 112.93 μM. gp120-IN-2 dose-dependently shows cytotoxicity in SUP-T1 cells [1]. | |||
T60519 | Antiparasitic agent-4 | ||
Antiparasitic agent-4 (compound 4q) exhibits high antiparasitic activity with IC50 of 8.51 μM for Leishmania infantum (L. infantum) and IC50 of 2.20 μM for Trypanosoma cruzi ( T. cruzi ). Antiparasitic agent-4 is also cy... | |||
T60810 | Influenza virus-IN-2 | ||
Influenza virus-IN-2 (compound 19) has anti-influenza A virus activities that is a potent inhibitor of influenza virus with an CC 50 of 150.85 μM and EC 50 of 2.58 μM. Influenza virus-IN-2 concentration-dependently inhib... | |||
T60697 | Influenza virus-IN-1 | ||
Influenza virus-IN-1 (compound 14) exhibits anti-influenza A virus activities which is a potent inhibitor of influenza A virus with an CC 50 of >200 μM and EC 50 of 2.46 μM. Influenza virus-IN-1 exhibits a concentration ... | |||
T69081 | KRH-1636 | ||
KRH-1636 is an orally active, selective and extremely potent CXC chemokine receptor 4 antagonist. KRH-1636 exhibits a potent and selective anti-HIV-1 activity. KRH-1636 efficiently blocked replication of various T cell ... |
Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-02468 | CCL14 Protein, Human, Recombinant (aa 28-93, His) | Human | E. coli |
CCL14 Protein, Human, Recombinant (aa 28-93, His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 9.3 kDa and the accession number is Q16627-1. | |||
TMPY-02138 | Uteroglobin Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Uteroglobin Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 9.2 kDa and the accession number is P11684. | |||
TMPY-02257 | CCL14 Protein, Human, Recombinant (His) | Human | E. coli |
CCL14 Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 10.2 kDa and the accession number is Q16627-1. | |||
TMPY-02328 | Uteroglobin Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
Uteroglobin Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 9.8 kDa and the accession number is Q06318. | |||
TMPJ-00018 | CCL16 Protein, Human, Recombinant | Human | E. coli |
CCL16 is a member of CC chemokine family. CCL16 cDNA encodes a 120 amino acid peptide along with a 23 amino acids signal peptide that is cleaved to generate 97 amino acid protein. CCL16 is distantly related to other CC c... | |||
TMPK-00896 | CCR8 Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
CC chemokine receptor (CCR) 8 (previously called CKR-L1 or TER1 and designated CD198), which is expressed on Th2 cells and eosinophils, has been implicated in allergic diseases. CCR8 may regulate monocyte chemotaxis and ... | |||
TMPK-00897 | CCR8 Protein, Human, Recombinant (mFc) | Human | HEK293 Cells |
CC chemokine receptor (CCR) 8 (previously called CKR-L1 or TER1 and designated CD198), which is expressed on Th2 cells and eosinophils, has been implicated in allergic diseases. CCR8 may regulate monocyte chemotaxis and ... | |||
TMPK-01316 | CCR8 Protein, Cynomolgus, Recombinant (mFc) | Cynomolgus | HEK293 Cells |
CC chemokine receptor (CCR) 8 (previously called CKR-L1 or TER1 and designated CD198), which is expressed on Th2 cells and eosinophils, has been implicated in allergic diseases. CCR8 may regulate monocyte chemotaxis and ... | |||
TMPY-03779 | CCL27 Protein, Human, Recombinant (His) | Human | E. coli |
CCL27, also known as CTACK, is a small cytokine belonging to the CC chemokine family. Members of this family are proteins characterized by two adjacent cysteines. CCL27 is chemotactic for skin-associated memory T lymphoc... | |||
TMPY-05353 | CCL26 Protein, Human, Recombinant | Human | Baculovirus Insect Cells |
The eotaxin subfamily of CC chemokines consists of eotaxin-1/CCL11, eotaxin-2/CCL24 and eotaxin-3/CCL26. All eotaxins induce the trafficking of eosinophils to the sites of inflammation via CC chemokine receptor 3 (CCR3),... | |||
TMPJ-00009 | CCL2 Protein, Human, Recombinant | Human | E. coli |
The chemokine (C-C motif) ligand 2 (CCL2), also known as monocyte chemoattractant protein (MCP)-1 and small inducible cytokine A2 (SCYA2)), is a small cytokine that belongs to the CC chemokine family responsible for mono... | |||
TMPJ-00873 | CCL3L1 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
C-C Motif Chemokine 3-Like 1 (CCL3L1) is a secreted protein that belongs to the intercrine beta (chemokine CC) family. CCL3L1 is a ligand for CCR1, CCR3 and CCR5. CCL3L1 binds to several chemokine receptors including che... | |||
TMPJ-00831 | CCL3 Protein, Mouse, Recombinant (His) | Mouse | E. coli |
C-C Motif Chemokine 3 (MIP-1 alpha,CCL3 ) is a member of the beta or CC subfamily of chemokines and is closely related to CCL4/MIP-1 beta. CCL3 expression can be induced in a variety of hematopoietic cells, fibroblasts, ... | |||
TMPY-04451 | AMPK (G1/B1/A1) Heterotrimer Protein, Human, Recombinant (His & GST) | Human | Baculovirus Insect Cells |
AMPK (G1/B1/A1) Heterotrimer Protein, Human, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 160 kDa and the accession number is P54619-1&Q9Y478-1&... | |||
TMPY-03745 | CD3D & CD3E Heterodimer Protein, Human, Recombinant (Flag & His) | Human | HEK293 Cells |
CD3D & CD3E Heterodimer Protein, Human, Recombinant (Flag & His) is expressed in HEK293 mammalian cells with Flag and His tag. The predicted molecular weight is 31.05 kDa and the accession number is P04234-1&P07766-1. | |||
TMPY-03878 | Integrin alpha V beta 6 Protein, Human, Recombinant (Flag & His) | Human | HEK293 Cells |
Integrin alpha V beta 6 Protein, Human, Recombinant (Flag & His) is expressed in HEK293 mammalian cells with Flag and His tag. The predicted molecular weight is 190.4 kDa and the accession number is P06756-1&P18564-1. | |||
TMPY-02501 | CD3D & CD3E Heterodimer Protein, Human, Recombinant | Human | HEK293 Cells |
CD3D & CD3E Heterodimer Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 77.5 kDa and the accession number is P04234-1&P07766-1. | |||
TMPK-01151 | MXRA8 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Mxra8 is a recently described receptor for multiple alphaviruses, including Chikungunya (CHIKV), Mayaro (MAYV), Ross River (RRV), and O'nyong nyong (ONNV) viruses. MXRA8 Protein, Human, Recombinant (His) is expressed in ... | |||
TMPY-04262 | B7-H3 Protein, Human, Recombinant (His), Biotinylated | Human | HEK293 Cells |
B7-H3 Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 48 kDa and the accession number is Q5ZPR3-1. | |||
TMPY-04069 | Neurotrophin 3 Protein, Human, Recombinant | Human | E. coli |
NTF3 (Neurotrophin 3) is a Protein Coding gene. The protein encoded by this gene is a member of the neurotrophin family, that controls the survival and differentiation of mammalian neurons. This protein is closely relate... | |||
TMPY-04753 | IRE1 Protein, Human, Recombinant (aa 465-977) | Human | Baculovirus Insect Cells |
IRE1 Protein, Human, Recombinant (aa 465-977) is expressed in Baculovirus insect cells. The predicted molecular weight is 58.3 kDa and the accession number is O75460-1. | |||
TMPY-00772 | DC-SIGN Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
DC-SIGN Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 65.8 kDa and the accession number is Q9NNX6-1. | |||
TMPY-00586 | CLEC-2 Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 Cells |
CLEC-2 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 49.1 kDa and the accession number is Q9JL99-1. | |||
TMPY-05239 | HER2/ERBB2 Protein, Human, Recombinant , Biotinylated | Human | HEK293 Cells |
HER2/ERBB2 Protein, Human, Recombinant , Biotinylated is expressed in HEK293 mammalian cells. The predicted molecular weight is 70 kDa and the accession number is P04626-1. | |||
TMPY-04922 | FAP Protein, Human, Recombinant (His), Biotinylated | Human | HEK293 Cells |
FAP Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 87.2 kDa and the accession number is Q12884-1. | |||
TMPY-03383 | IL-7 Protein, Human, Recombinant | Human | E. coli |
IL-7 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 17.5 kDa and the accession number is P13232-1. | |||
TMPY-03481 | IL-1R2 Protein, Human, Recombinant | Human | HEK293 Cells |
IL-1R2 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 38.4 kDa and the accession number is P27930-1. | |||
TMPY-04925 | CD8 beta Protein, Human, Recombinant, Biotinylated | Human | HEK293 Cells |
CD8 beta Protein, Human, Recombinant, Biotinylated is expressed in HEK293 mammalian cells. The predicted molecular weight is 17.6 kDa and the accession number is P10966-1. | |||
TMPY-04970 | TIGIT Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
TIGIT Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 39.2 kDa and the accession number is Q495A1-1. | |||
TMPY-01776 | Carboxylesterase 2/CES2 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Carboxylesterase 2/CES2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 60.4 kDa and the accession number is O00748-1. | |||
TMPY-00991 | LIFR Protein, Human, Recombinant (His) | Human | HEK293 Cells |
LIFR Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 91 kDa and the accession number is P42702-1. | |||
TMPY-04413 | IRE1 Protein, Human, Recombinant (aa 465-977, His & GST) | Human | Baculovirus Insect Cells |
IRE1 Protein, Human, Recombinant (aa 465-977, His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 86 kDa and the accession number is O75460-1. | |||
TMPY-00399 | HER3/ERBB3 Protein, Human, Recombinant | Human | HEK293 Cells |
HER3/ERBB3 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 69.3 kDa and the accession number is P21860-1. | |||
TMPK-01074 | CD163 Protein, Human, Recombinant (His & Avi) | Human | HEK293 Cells |
The hemoglobin (Hb) scavenger receptor, CD163, is a macrophage-specific protein and the upregulated expression of this receptor is one of the major changes in the macrophage switch to alternative activated phenotypes in ... | |||
TMPY-02361 | VEGFR2/KDR Protein, Human, Recombinant (His) | Human | HEK293 Cells |
VEGFR2/KDR Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 84.6 kDa and the accession number is P35968-1. | |||
TMPY-00740 | SDF-1 Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
SDF-1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 35.2 kDa and the accession number is P48061-1. | |||
TMPY-04799 | IFNAR2 Protein, Human, Recombinant (His), Biotinylated | Human | HEK293 Cells |
IFNAR2 Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.2 kDa and the accession number is P48551-1. | |||
TMPY-03363 | C-Reactive Protein Protein, Human, Recombinant | Human | HEK293 Cells |
C-Reactive Protein Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 23 kDa and the accession number is P02741-1. | |||
TMPY-00947 | VCAM-1 Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
VCAM-1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 100.8 kDa and the accession number is P19320-1. | |||
TMPY-00972 | FGFR2 Protein, Human, Recombinant (His & hFc) | Human | HEK293 Cells |
FGFR2 Protein, Human, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 67.6 kDa and the accession number is P21802-1. | |||
TMPY-02813 | ErbB4 Protein, Human, Rhesus, Recombinant (His) | Human,Rhesus | HEK293 Cells |
ErbB4 Protein, Human, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 71.1 kDa and the accession number is Q15303-1. | |||
TMPY-01853 | SIRP gamma Protein, Human, Recombinant (His) | Human | HEK293 Cells |
SIRP gamma Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 38.5 kDa and the accession number is Q9P1W8-1. | |||
TMPY-01827 | CD30/TNFRSF8 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
CD30/TNFRSF8 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 40 kDa and the accession number is P28908-1. | |||
TMPY-00203 | LOXL2 Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
Lysyl oxidase homolog 2, also known as Lysyl oxidase-like protein 2, Lysyl oxidase-related protein 2, Lysyl oxidase-related protein WS9-14 and LOXL2, is a secreted protein that belongs to the lysyl oxidase family. LOXL2 ... | |||
TMPY-02327 | HGF Protein, Human, Recombinant | Human | CHO Cells |
HGF Protein, Human, Recombinant is expressed in CHO mammalian cells. The predicted molecular weight is 79.7 kDa and the accession number is P14210-1. | |||
TMPY-02836 | MFGE8 Protein, Human, Recombinant (His) | Human | Baculovirus Insect Cells |
MFGE8 Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 42 kDa and the accession number is Q08431-1. | |||
TMPY-01305 | OSMR Protein, Human, Recombinant (His) | Human | HEK293 Cells |
OSMR Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 82.6 kDa and the accession number is Q99650-1. | |||
TMPY-05364 | CD8 alpha Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
CD8 alpha Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 44.3 kDa and the accession number is P01732-1. | |||
TMPY-03958 | TGF alpha Protein, Human, Recombinant | Human | E. coli |
The miR-137 served as a tumor suppressor in non-small cell lung cancer (NSCLC) and its suppressive effect is mediated by repressing TGFA expression. TGFA gene expression was significantly higher in tumor tissues compared... | |||
TMPY-01851 | CD73 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
CD73 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 59.2 kDa and the accession number is P21589-1. | |||
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Cat No. | Product Name | ||
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L7600 | Chemokine Inhibitor Library | 59 compounds | |
A unique collection of 59 chemokines or chemokine receptors targeted compounds for high throughput and high content screening; |